Active Ingredient In Roundup “The Most Important Causal Factor” In Celiac Disease And Gluten Intolerance

Glyphosate, Pathways To Modern Diseases II: Celiac Sprue And Gluten Intolerance, Interdisciplinary Toxicology, December 2013

Celiac disease and gluten intolerance are just one part of the glyphosate picture. But let’s just look at them for a moment:

So, as glyphosate/Roundup use increased, the incidence of celiac disease and intestinal infections increased. The paper explained why the increase in disease was not simply due to increased reporting from better diagnostic tools.

This is a big paper, lots of mechanisms, 271 references. There’s a lot here. This is from the abstract:

Celiac disease, and, more generally, gluten intolerance, is a growing problem worldwide, but especially in North America and Europe, where an estimated 5% of the population now suffers from it. Symptoms include nausea, diarrhea, skin rashes, macrocytic anemia and depression. It is a multifactorial disease associated with numerous nutritional deficiencies as well as reproductive issues and increased risk to thyroid disease, kidney failure and cancer.

So, celiac disease is on the rise, in parallel to glyphosate/Roundup use. They ruled out disease increase from increased reporting due to better diagnostic tools.

Here, we propose that glyphosate, the active ingredient in the herbicide, Roundup®, is the most important causal factor in this epidemic.

Fish exposed to glyphosate develop digestive problems that are reminiscent of celiac disease.

Celiac disease is associated with imbalances in gut bacteria that can be fully explained by the known effects of glyphosate on gut bacteria.

Characteristics of celiac disease point to impairment in many cytochrome P450 enzymes, which are involved with detoxifying environmental toxins, activating vitamin D3, catabolizing vitamin A, and maintaining bile acid production and sulfate supplies to the gut. Glyphosate is known to inhibit cytochrome P450 enzymes.

Deficiencies in iron, cobalt, molybdenum, copper and other rare metals associated with celiac disease can be attributed to glyphosate’s strong ability to chelate these elements.

Deficiencies in tryptophan, tyrosine, methionine and selenomethionine associated with celiac disease match glyphosate’s known depletion of these amino acids.

Celiac disease patients have an increased risk to non-Hodgkin’s lymphoma, which has also been implicated in glyphosate exposure.

Reproductive issues associated with celiac disease, such as infertility, miscarriages, and birth defects, can also be explained by glyphosate.

Glyphosate residues in wheat and other crops are likely increasing recently due to the growing practice of crop desiccation just prior to the harvest.

We argue that the practice of “ripening” sugar cane with glyphosate may explain the recent surge in kidney failure among agricultural workers in Central America.

We conclude with a plea to governments to reconsider policies regarding the safety of glyphosate residues in foods.

We have to stop consuming – breathing, eating, drinking – glyphosate. As I have been saying for years, buying organic is a smoke screen. There’s so much of this in use now that it contaminates organic crops. Remember this? — > Bob’s Red Mill Faces Class Action Lawsuit over Glyphosate Weedkiller Contamination. In one study, some of the highest levels of glyphosate were found in organic eggs because glyphosate bioaccumulates.

The EPA is trying to weasel out of responsibility by setting limits for glyphosate in food that are ridiculously high. Endocrine disruptors like glyphosate, according to the Endocrine Society, cause abnormalities at “even infinitesimally low levels.” Lower doses, in fact, are more hormonally disrupting than higher doses.

In July of this year, a statement by the International Federation of Gynecology and Obstetrics (FIGO) concluded: “We recommend that glyphosate exposure to populations should end with a full global phase out.”

This is what we’re up against:

3 thoughts on “Active Ingredient In Roundup “The Most Important Causal Factor” In Celiac Disease And Gluten Intolerance

    1. Bix Post author

      So much suffering … humans, animals, ecosystems. For what? Why, when we discover a chemical is harmful, a way of growing food is harmful, a way of heating homes and fueling vehicles is harmful, don’t we change course? Why?


  1. Marj

    This is so interesting (and disturbing) to me. I was diagnosed with celiac disease in 2011 and have adhered to a gluten-free diet since. The most outrageous thing (as you say) is that nothing is changed re the chemical and its impact on so many life forms. A similar outrage is the recent publicity regarding the many harms resulting from a DuPont chemical in West Virginia and there again nothing is being changed.



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