Drugs That Reduce Stomach Acid Secretion – Proton Pump Inhibitors (PPIs) – Increase Risk For Diabetes

The single most important thing you can do to prevent diabetes is lose weight. It almost doesn’t matter how – diet, exercise, fasting, surgery. I advocate a low-fat, plant-based diet because it improves health in so many other ways. But it’s not the only way to lose weight.

There are other factors that increase risk for diabetes besides being overweight … family history, having diabetes while pregnant, air pollution, exposure to endocrine disruptors (like BPA) and other environmental pollutants. And now, taking PPIs:

Regular Use Of Proton Pump Inhibitors And Risk Of Type 2 Diabetes: Results From Three Prospective Cohort Studies, BMJ Gut, September 2020

Conclusions: Regular use* of proton pump inhibitors (PPIs) was associated with a higher risk of type 2 diabetes and the risk increased with longer duration of use. Physicians should therefore exercise caution when prescribing PPIs, particularly for long-term use.

* Regular use was defined as 2 or more times a week

Regular Use Of Acid Reflux Drugs Linked To Heightened Risk Of Type 2 Diabetes, BMJ Newsroom, 28 September 2020

PPIs are used to treat acid reflux, peptic ulcers, and indigestion. They are among the top 10 most commonly used drugs worldwide. Long-term use has been linked to an increased risk of bone fractures, chronic kidney disease, gut infections and stomach cancer.

A mounting body of evidence suggests that changes in the type and volume of bacteria in the gut (the microbiome) may help explain the associations found between PPI use and an increased risk of developing diabetes.

Examples of PPIs:
Omeprazole (Prilosec)
Lansoprazole (Prevacid)
Esomeprazole (Nexium)

Unidentified Aerial Phenomenon (UAP), Scotland 1990

Another unusual story.

1990: A 100-foot-wide diamond-shaped object was seen by 2 hikers at Calvine, Scotland. They took 6 photographs which the UK’s Ministry of Defence said, after investigation, had not been faked (above is a reconstruction).  The object hovered silently for 10 minutes before “accelerating away at immense speed – vertically.” A military fighter jet can be seen in the background.

Nick Pope just published this article:

I’ve Seen The Top Secret Photos Showing ‘Britain’s Most Significant UFO Sighting’ – They Left Us Shell-Shocked, Nick Pope, Oct 10 2020

Who is Nick Pope? He worked for the UK’s Ministry of Defence (MoD). From 1991 to 1994 he ran their UAP program:

I worked for the MOD for 21 years. From 1991 to 1994, I was posted to a division where my duties included undertaking these investigations. It was a fascinating job, to say the least.

The article discusses the Calvine Incident, and its soon-to-be-released (January 2021) high-definition color photographs which the MOD kept classified for 30 years. The image above is considered an accurate reconstruction of one of the hiker’s photographs, based on actual MOD line drawings and Nick Pope’s memory.

The reason for this interest in a 30-year-old sighting? It’s being reported that the MOD has decided to block release of the photos for another 50 years.

Excerpts:

In the cult sci-fi series The X-Files, Fox Mulder has a poster of a UFO on the wall of his basement office. Underneath are the words “I want to believe”.

In the Ministry of Defence office, which served as the nerve centre of the UK’s UFO project, we had something very similar. But our picture was real.

Most UFO photos are either obvious fakes, or blurry and indistinct – a vague light in the night sky, or a fuzzy dot in the distance.

Not this one. It was up-close-and-personal, had been taken in broad daylight, and showed a large diamond-shaped craft.

I soon got the story out of my predecessor and read the file myself. It was an extraordinary tale: two men had been out hiking near Calvine in Scotland.

Suddenly, they’d seen a massive UFO hanging in the sky above their heads, silent, motionless and menacing. Awestruck, they shot off six photographs before the object accelerated away at immense speed – vertically!

The shell-shocked witnesses sent the photos to a Scottish newspaper and a journalist contacted the MoD press office, looking for a comment.

Somehow – perhaps using a D-Notice or perhaps using some real-life Men-in-Black trickery – someone at the MoD managed to extract all the photos and the negatives from the newspaper, who never got them back.

The MoD’s technical wizards leapt into action. The images were enlarged and analyzed, using the full resources and capabilities of intelligence community specialists.

Even now, years after these events, I can’t discuss the details of this process, as so much of the information is top secret.

The analysis was nothing short of sensational. The photos hadn’t been faked.

They showed a structured craft of unknown origin, unlike any conventional aircraft. There was no fuselage, no wings, no tail, no engines and no markings of any sort.

Because the photos had been taken in daylight with the surrounding countryside visible, MoD boffins could make some calculations about the mystery object’s size. It turned out to be nearly 100 feet in diameter.

The MoD’s standard line on UFOs was that the phenomenon was of ‘no defence significance’ – a meaningless Whitehall soundbite that meant whatever we wanted it to mean.

At best it was misleading and at worst, it was a downright lie.

We consistently played down the true level of our interest in UFOs, telling parliament, the media and the public that the subject was of little interest, while all the time, behind closed doors, we struggled to make sense of cases like the Calvine incident.

Despite an extensive investigation, we never found a definitive explanation for what was seen at Calvine.

Like the Tic Tac, this is a well-documented sighting of an unusual aerial phenomenon that remains unexplained.

____________________
Related:British MOD Buries UFO Dossier For Another 50 Years

COVID-19 Is Now The Third Leading Cause Of Death In The US

COVID is now the third leading cause of death in the US, except for a spike in April when it was the leading cause of death, beating out heart disease and cancer.

The top 10 leading causes of death in the US in 2018, the latest year for which data is available were:

Heart disease (655,381)
Cancer (599,274)
Unintentional injury (167,127)
Chronic lower respiratory disease (159,486)
Stroke (147,810)
Alzheimer’s disease (122,019)
Diabetes (84,946)
Flu and pneumonia (59,120) (34,000 for flu alone 2018-2019 season)
Nephritis (51,386)
Suicide (48,344)

(the CDC succumbs to industry pressure by not listing medical errors, which rank among the top three causes, if not the top cause.)

As of this writing there were 212,789 deaths attributed to Covid-19 in the US this year, placing COVID-19 firmly in the third position.

The flu killed 34,000 people last year. That figure is inflated because not everyone who dies of flu has indeed been tested for influenza. Covid-19 has killed over 212,000 people so far this year. That figure underrepresents deaths. It fails to account for people with medical conditions who die because hospitals are overwhelmed with COVID-19. And the year isn’t up. So, Covid-19 is considerably worse than flu.

On 21 September, the President said about COVID-19, “It affects virtually nobody.” As of this writing, there have been over 7.6 million Americans who tested positive for COVID-19.

On 8 October, the President said, “When you catch it, you get better. … That’s what happens, you get better.” As you can see, 212,789 people did not get better. They died.

The President seems delusional.

1994: Reversal of Coronary Atherosclerosis And Prevention Of Coronary Events With Low-Fat Diet, Cholesterol Reduction

A low-fat diet and cholesterol reduction. They were the prescription for heart disease in 1994, along with smoking cessation and activity. They were the prescription before 1994 and since then too, because they worked. The only thing that has changed in recent years is the influx of money from parties that would suffer: the meat industry, the dairy and egg industries, and other industries with a stake in Big Food. They advertised, they influenced USDA Dietary Guidelines, and, the most insidious? They published studies in peer-reviewed journals to sow doubt.

Here we go. 1994. How to avoid a heart attack without drugs or surgery:

Reversal of Coronary Atherosclerosis, Clinical Promise as the Basis for Noninvasive Management of Coronary Artery Disease, K. Lance Gould MD, Circulation, 1994

Angioplasty, stents, and bypass surgery fix local problems. But narrowing of vessels is a systemic problem, it doesn’t just happen in one or two places:

Coronary atherosclerosis is a diffuse process in the entire epicardial coronary artery tree, subject throughout to the risk of plaque rupture and associated coronary events in the absence of vigorous risk factor management.

So, what is vigorous risk factor management? Specifically:

Very low fat diets (less than 10% of calories as fat), tend to show greater benefit on regression or prevention of events than studies with less vigorous intervention.

These new approaches to the treatment of coronary atherosclerosis provide a relatively low-cost alternative to traditional invasive approaches that markedly decreases myocardial infarction, death, balloon angioplasty, or bypass surgery in patients with moderate or severe coronary artery stenoses.

For optimal probability of partial reversal and preventing coronary events with a certainty comparable to or better than invasive alternatives, a reversal regimen should achieve lean body mass, total cholesterol of 140 mg/dl or below, low-density lipoprotein below 80 to 90 mg/dl, HDL 45 mg/dl or above, and absence of smoking. At these goals, coronary events are simply uncommon.

Here’s a hearty low-fat vegetable soup to get you started, or to keep you going, or just because it tastes good:

Lentil Vegetable Soup, Forks Over Knives, May 2014

(I like these sped-up videos. You can get the whole idea in less than a minute.)

Can You Get Too Much Zinc?

Lots of people have been taking supplemental zinc to boost their immune systems during the pandemic. It’s possible to get too much:

NIH – Zinc Consumer Fact Sheet

Signs of too much zinc include nausea, vomiting, loss of appetite, stomach cramps, diarrhea, and headaches. When people take too much zinc for a long time, they sometimes have problems such as low copper levels, lower immunity, and low levels of HDL cholesterol (the “good” cholesterol).

NIH – Zinc Health Professional Fact Sheet

Reductions in a copper-containing enzyme, a marker of copper status, have been reported with even moderately high zinc intakes of approximately 60 mg/day for up to 10 weeks.

The doses of zinc used in the AREDS [Age-Related Eye Disease Study] study (80 mg per day of zinc in the form of zinc oxide for 6.3 years, on average) have been associated with a significant increase in hospitalizations for genitourinary causes, raising the possibility that chronically high intakes of zinc adversely affect some aspects of urinary physiology .

What is high for you may not be high for someone else. Glancing at the RDA’s, anything over 11 mg/day doesn’t appear necessary and may be harmful – especially if taken repeatedly.

It’s Spider Season!

‘Human-Sized’ Spider Web Found In Missouri Forest, Independent, 4 October 2020

A giant spider web was discovered by the Missouri Department of Conservation’s Francis Skalicky off a trail near Springfield.

“Those are the kind that literally ‘catch’ people if they walk through them at night lol,” said Facebook commenter Jennifer Duffy Russell.

It was woven by an orb-weaver spider:

“Webs are built at dusk and used for snaring prey during the night. At dawn, the spider reingests the strands (along with moisture that has collected on it as dew) and recycles the nutrients in making the next web,” the Conservation Department said.

Army’s New Recommendation: Aggressive Napping

Sleeping Leopard, South Luangwa National Park, Zambia. Source: Will Burrard-Lucas

The Army Rolls Out a New Weapon: Strategic Napping, New York Times, 1 October 2020

Excerpts:

On Wednesday, the Army released new guidelines for optimal soldier performance — and they include strategic and aggressive napping.

The recommendation is part of an overhaul of the Army’s physical fitness training field manual, which was rebranded this week as the FM 7-22 Holistic Health and Fitness manual. No longer is the guide focused entirely on grueling physical challenges like long ruck marches and pull-ups. Now it has chapters on setting goals, visualizing success, “spiritual readiness” and, yes, the art of the nap.

“Soldiers can use short, infrequent naps to restore wakefulness and promote performance,” the new manual advises. “When routinely available sleep time is difficult to predict, soldiers might take the longest nap possible as frequently as time is available.”

It is the first update to the manual in eight years, and it reflects growing scientific evidence that peak physical performance includes more than just physical training.

The manual also has updates on running techniques to avoid injury, and a section on the importance of spirituality, with entries on meditation, journaling and how the “act of serving others” helps some soldiers realize the “interconnectedness of all things and people.”

“The Army has always had an internal dynamic that real men don’t need sleep and can just push on, and it’s incredibly stupid,” said Lt. Gen. David Barno, who was commander of combined forces in Afghanistan from 2003 to 2005.

If it’s good enough for the Army…