This is an interesting paper. It describes mechanisms by which the mRNA vaccine can cause Bell’s palsy (one side of face weakens and droops), shingles, myocarditis (heart inflammation), and cancer (disturbs DNA repair mechanisms). It can cause early, undetected cancers or those in remission to grow aggressively.

Innate immune suppression by SARS-CoV-2 mRNA vaccinations: The role of G-quadruplexes, exosomes, and MicroRNAs, Food and Chemical Toxicology, June 2022

Highlights

• mRNA vaccines promote sustained synthesis of the SARS-CoV-2 spike protein.
• The spike protein is neurotoxic, and it impairs DNA repair mechanisms.
• Suppression of type I interferon responses results in impaired innate immunity.
• The mRNA vaccines potentially cause increased risk to infectious diseases and cancer.
• Codon optimization results in G-rich mRNA that has unpredictable complex effects.

From the abstract:

The mRNA SARS-CoV-2 vaccines were brought to market in response to the public health crises of Covid-19. The utilization of mRNA vaccines in the context of infectious disease has no precedent. The many alterations in the vaccine mRNA hide the mRNA from cellular defenses and promote a longer biological half-life and high production of spike protein. However, the immune response to the vaccine is very different from that to a SARS-CoV-2 infection.

In this paper, we present evidence that vaccination induces a profound impairment in type I interferon signaling, which has diverse adverse consequences to human health. Immune cells that have taken up the vaccine nanoparticles release into circulation large numbers of exosomes containing spike protein along with critical microRNAs that induce a signaling response in recipient cells at distant sites.

We also identify potential profound disturbances in regulatory control of protein synthesis and cancer surveillance. These disturbances potentially have a causal link to neurodegenerative disease, myocarditis, immune thrombocytopenia, Bell’s palsy, liver disease, impaired adaptive immunity, impaired DNA damage response and tumorigenesis. We show evidence from the VAERS database supporting our hypothesis.

This is their graphical abstract. Note the pathway for how the vaccine causes reactivation of latent viruses, such as viruses that cause shingles (herpes zoster), Bell’s palsy (herpes simplex), hepatitis.

One basic concept I walk away with is … the mRNA vaccines suppress “type I IFN signaling”. IFN stands for interferon, and this paper is a master class in the interferons (proteins that contribute to immunity).

It’s not light reading. I’ve visited it on and off since its early online release in April. There’s a lot here. I’ve learned a lot.

I’m posting it so I can easily refer to it later and for anyone else interested in the topic.