Could ADE (Antibody-Dependent Enhancement) Be Responsible For Spike In Severe Cases In Vaccinated?

The extraordinary number of serious cases of COVID in Israel – in vaccinated people – may be explained in part, according to Dr. Robert Malone (the inventor of mRNA vaccines), by ADE: antibody-dependent enhancement:

Antibody-dependent enhancement (ADE) is a phenomenon in which binding of a virus to suboptimal antibodies enhances its entry into host cells, followed by its replication.

ADE may cause enhanced respiratory disease and acute lung injury after respiratory virus infection.

ADE along with type 2 T helper cell-dependent mechanisms may contribute to a development of the vaccine associated disease enhancement (VADE), which is not limited to respiratory disease.

Some vaccine candidates that targeted coronaviruses, RSV virus and Dengue virus elicited VADE, and were terminated from further development or became approved for use only for patients who have had those viruses before.

So, vaccines may promote the development of poorly neutralizing antibodies which may enhance subsequent infection. Previous reports from SARS and MERS-CoV document this.

In Israel:
“95% of the severe patients are vaccinated”.
“85-90% of the hospitalizations are in Fully vaccinated people.”
“We are opening more and more COVID wards.”
“The effectiveness of the vaccine is waning/fading out”
(Dr. Kobi Haviv, earlier today on Chanel 13 @newsisrael13 )

2 thoughts on “Could ADE (Antibody-Dependent Enhancement) Be Responsible For Spike In Severe Cases In Vaccinated?

  1. Milo Mac

    This is a very important question. As Pfizer continues to wane, it will become clear if this is happening.

    In the Pfizer EUA docs, the FDA entities ADE as a unknown risk as the vaccines wane. They knew it was a possibilities.

    See page 49.

    Vaccine-enhanced disease
    Available data do not indicate a risk of vaccine-enhanced disease, and conversely suggest effectiveness against severe disease within the available follow-up period. However, risk of vaccine-enhanced disease over time, potentially associated with waning immunity, remains unknown and needs to be evaluated further in ongoing clinical trials and in observational studies that could be conducted following authorization and/or licensure.


  2. Pingback: Good speech by an epidemiologist critical of the ‘vaccine’ for being a toxin with unknown long-term effects and “unsafe for human use.” – Think for Yourself

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