Butyrate Really Is Good For You, You Get It By Eating Starch


Eat starch. This is a photo of my fat-free potato salad. Here’s the recipe.

Before I leave the topic of butyrate (Butyrate Is Good For The Colon, But You Can’t Get It There By Eating Butter), I want to post some of the paper that Sammy Pepys drew our attention to:

Potential Beneficial Effects Of Butyrate In Intestinal And Extraintestinal Diseases, World Journal of Gastroenterology, 2011.

The multiple beneficial effects on human health of the short-chain fatty acid butyrate, synthesized from non-absorbed carbohydrate by colonic microbiota, are well documented. At the intestinal level, butyrate plays a regulatory role on the transepithelial fluid transport, ameliorates mucosal inflammation and oxidative status, reinforces the epithelial defense barrier, and modulates visceral sensitivity and intestinal motility. In addition, a growing number of studies have stressed the role of butyrate in the prevention and inhibition of colorectal cancer. At the extraintestinal level, butyrate exerts potentially useful effects on many conditions, including hemoglobinopathies, genetic metabolic diseases, hypercholesterolemia, insulin resistance, and ischemic stroke. The mechanisms of action of butyrate are different; many of these are related to its potent regulatory effects on gene expression. These data suggest a wide spectrum of positive effects exerted by butyrate, with a high potential for a therapeutic use in human medicine.

Look at all these benefits! Why would you want to give them all up by avoiding starch?

I spoke about short-chain fatty acids in general and butyrate in particular back when I wrote about resistant starch, starting in 2005, 11 years ago! (You can go to my old blog at http://fanaticcook.blogspot.com/ and type in “resistant starch” in the search field to find those posts.) More has been uncovered about its benefits since then. How do you get butyrate? By eating starch.

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