Flu Shot: Cochrane Collaboration Still Discourages It

FluShots2015_2

Flu shots have been shown to be largely ineffective, but a financial boon for businesses that sell them.

It’s that time of year again for me to wrestle with the idea of getting a flu shot. It hasn’t been getting my vote. I base that vote on the work the of The Cochrane Collaboration, who are:

A global independent network of researchers, professionals, patients, carers, and people interested in health.

Cochrane contributors – 37,000 from more than 130 countries – work together to produce credible, accessible health information that is free from commercial sponsorship and other conflicts of interest. Many of our contributors are world leaders in their fields – medicine, health policy, research methodology, or consumer advocacy – and our groups are situated in some of the world’s most respected academic and medical institutions.

Our work is recognized as representing an international gold standard for high quality, trusted information.

Two things there … free from commercial interests and science-based. The buck stops with Cochrane. Here’s what they say:

Summary 2014: Vaccines For Preventing Influenza In Healthy Adults, Cochrane, March 2014
Study 2014: Vaccines To Prevent Influenza In Healthy Adults, Cochrane Library, March 2014
Study 2010: Vaccines For Preventing Influenza In Healthy Adults, Cochrane Library, July 2010

After reviewing 90 reports of 116 studies, the largest collection of randomized evidence on influenza, they say it doesn’t do much good, and can cause harm:

The preventive effect of parenteral inactivated influenza vaccine on healthy adults is small: at least 71 people would need vaccination to prevent one case of influenza.

Vaccination shows no appreciable effect on working days lost or hospitalisation.

Myalgia is significantly associated with vaccination, as well as systemic fever, headache, fatigue or indisposition and malaise.

They outright discouraged its use a couple years ago (2010 study above), based on much of the same data, but I’m guessing some profit-making entity fought against such a straightforward conclusion:

The results of this review seem to discourage the utilisation of vaccination against influenza in healthy adults as a routine public health measure.

The reason you see signs everywhere for getting a flu shot, the reason you hear physicians recommending it, is because drug companies make money when people buy their vaccines. So, drug companies push these shots. They disseminate biased studies, many of which they fund, to health professionals and organizations:

This [Cochrane] review includes 90 studies, 24 of which (26.7%) were funded totally or partially by industry. Out of the 48 RCTs, 17 were industry-funded (35.4%).

From the 2010 study:

It is now known that industry funding of influenza vaccines studies determines publication in high prestige journals and higher citation rates than other types of funding. In addition industry funding is associated with optimistic conclusions.

Conclusions favorable to the use of influenza vaccines were associated with higher risk of bias. In these studies the authors made claims and drew conclusions unsupported by the data they presented. In addition, industry funded studies are more likely to have favorable conclusions and be published in significantly higher impact factor journals and have higher citation rates than non-industry funded studies. This difference is not explained by either their size or methodological quality.

Here are a few more tidbits:

  • Over 200 viruses cause influenza. The flu vaccine covers “at best” 10% of those.
  • 2.4% of unvaccinated people versus 1.1% of vaccinated people developed influenza symptoms. So, close to 98% of people who didn’t get a flu shot avoided getting the flu on their own.
  • “We found no evidence that vaccinations prevent viral transmissions.” (Jefferson, 2010)
  • “Studies funded from public sources were significantly less likely to report conclusions favorable to the vaccines.” (Jefferson, 2010)

You’d have to vaccinate 71 people to prevent one case of flu, even then you don’t get rid of all symptoms. And getting a flu shot won’t reduce lost work time or hospitalizations.

If you’re a healthy adult, it’s a decision that makes itself, isn’t it?

__________
Related:
Johns Hopkins Scientist Reveals Shocking Report On Flu Vaccines, 2 December 2015
Influenza: Marketing Vaccine By Marketing Disease, BMJ, 2013
The Benefits of Flu Shots Oversold, McDougall Newsletter, November 2015

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